I knew the laptop screen wasn't the best and compared to my Mac's Retina display it's basically a stone age monitor, but I still wouldn't accept the terrible text rendering in Chrome. After a bit of research it turned out that by turning off text antialiasing it was possible to improve text display quality.
To disable antialiasing, in Chrome, navigate to chrome://flags. Then look for 'LCD text anti-aliasing' and set it to Disabled.
Making this change on my 100S made a huge difference.